Treatment plan optimization incorporating respiratory motion

Treatment plan optimization incorporating respiratory motion.

Similar to conventional conformal radiotherapy, during lung tomotherapy, a motion margin has to be set for respiratory motion. Consequently, large volume of normal tissue is irradiated by intensive radiation. To solve this problem, we have developed a new motion mitigation method by incorporating target motion into treatment optimization. In this method, the delivery-breathing correlation is de...

Treatment plan optimization for rotating-shield brachytherapy

In this thesis, we aim to develop fundamentally new techniques and algorithms for efficiently computing rotating-shield brachytherapy (RSBT) treatment plans. We propose that these algorithms will pave the way for making RSBT available in clinical practices. RSBT is an intensity modulated high-dose-rate brachytherapy (HDR-BT) technique. Theoretically, RSBT offers advantages over the conventional...

Plan Optimization by Plan Rewriting

Planning by Rewriting (PbR) is a paradigm for efficient high-quality planning that exploits declarative plan rewriting rules and efficient local search techniques to transform an easy-to-generate, but possibly suboptimal, initial plan into a high-quality plan. In addition to addressing planning efficiency and plan quality, PbR offers a new anytime planning algorithm. The plan rewriting rules ca...

Ultrafast treatment plan optimization for volumetric modulated arc therapy (VMAT).

PURPOSE To develop a novel aperture-based algorithm for volumetric modulated are therapy (VMAT) treatment plan optimization with high quality and high efficiency. METHODS The VMAT optimization problem is formulated as a large-scale convex programming problem solved by a column generation approach. The authors consider a cost function consisting two terms, the first enforcing a desired dose di...

Control Plan Optimization